Alertness-enhancing drugs as a countermeasure
to fatigue in irregular work hours
by
Akerstedt T, Ficca G
IPM/Karolinska Institute,
Stockholm, Sweden.
Chronobiol Int 1997 Mar; 14(2):145-58

ABSTRACT

Irregular work/rest patterns frequently cause disturbed sleep and excessive sleepiness and accidents. This review is focused on four pharmacological countermeasures-the "new" drugs modafinil and pemoline, the traditional caffeine, and, as a reference, amphetamine. It is concluded that there is still too little data available to decide whether systematic use of alertness-enhancing drugs is feasible in occupational settings. D-Amphetamine is ruled out because of its abuse potential and mood effects. Modafinil and pemoline have not been tested in field situations, whereas caffeine certainly is used to improve alertness during work, but the use is spontaneous/ad hoc, and there is still a lack of data on its systematic application. Particularly, the optimal amount and pattern of administration need elucidation.

Stereotypies
Neurotoxicity
VTA/glutamate
CNS stimulants
Self-medication
Worms on speed
Dopamine uptake
Sleep-deprivation
Canine narcolepsy
Appetite suppressants
Methamphetamine psychosis
Methamphetamine/narcolepsy

Refs
and further reading

HOME
HedWeb
Nootropics
cocaine.wiki
Cannabis.net
Future Opioids
BLTC Research
MDMA/Ecstasy
Superhappiness?
Utopian Surgery?
The Good Drug Guide
The Abolitionist Project
The Hedonistic Imperative
The Reproductive Revolution
Critique of Huxley's Brave New World