Reinforcing effects of
methamphetamine in planarians
by
Kusayama T, Watanabe S
Department of Psychology,
Keio University,
Tokyo, Japan.
Neuroreport 2000 Aug 3;11(11):2511-3

ABSTRACT

Reinforcing properties of dopamine agonist, methamphetamine, for planarians were examined with the conditioned place preference (CPP) procedure. The planarians showed preference for the environment associated with methamphetamine administration. This reinforcing effect was antagonized by pretreatment with non-selective dopamine antagonist, haloperidol. Both selective D1 antagonist SCH23390 and selective D2 antagonist sulpiride also blocked the reinforcing effect of methamphetamine. These results suggest that reinforcing effects of dopaminergic drugs can be traced back to invertebrates such as planarians.

Goldfish
Adderall
Overdose
Pregnancy
Stereotypies
Neurotoxicity
VTA/glutamate
CNS stimulants
Self-medication
Dopamine uptake
Canine narcolepsy
Appetite suppressants
Methamphetamine psychosis
Methamphetamine/narcolepsy
Amphetamine and the angry mouse
Amphetamine withdrawal/depression

Refs
and further reading

HOME
HedWeb
Nootropics
cocaine.wiki
Cannabis.net
Future Opioids
BLTC Research
MDMA/Ecstasy
Superhappiness?
Utopian Surgery?
The Good Drug Guide
The Abolitionist Project
The Hedonistic Imperative
The Reproductive Revolution
Critique of Huxley's Brave New World